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Pregled bibliografske jedinice broj: 37102

Collision tumour in the pelvic cavity: rectal leiomyosarcoma and prostate adenocarcinoma


Pavelić, Jasminka; Lamovec, Janez; Novak, Janez; Gall-Trošelj, Koraljka; Kapitanović, Sanja; Pavelić, Krešimir
Collision tumour in the pelvic cavity: rectal leiomyosarcoma and prostate adenocarcinoma // Journal of Cancer Research and Clinical Oncology, 126 (2000), 95-100 (međunarodna recenzija, članak, znanstveni)


Naslov
Collision tumour in the pelvic cavity: rectal leiomyosarcoma and prostate adenocarcinoma

Autori
Pavelić, Jasminka ; Lamovec, Janez ; Novak, Janez ; Gall-Trošelj, Koraljka ; Kapitanović, Sanja ; Pavelić, Krešimir

Izvornik
Journal of Cancer Research and Clinical Oncology (0171-5216) 126 (2000); 95-100

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Collision tumour; Leiomyosarcoma; Prostatic; Adenocarcinoma
(Collision tumour; leiomyosarcoma; prostatic; adenocarcinoma)

Sažetak
We report a rare and, to our knowledge, as yet undescribed type of collision tumour - rectal leiomyosarcoma and prostate adenocarcinoma. Our study also provides the first data on molecular alterations{polymerase chain reaction/loss of heterozygosity (LOH) analysis} of the APC, NF-1, DCC, p53, nm23-H1 and BRCA-1 genes in the two components of the collision tumour. None of the genes examined in this study expressed LOH in the prostate carcinoma component of the collision tumour. By contrast, in the leiomyosarcoma component, LOH was found at the DCC and p53 genes, proving that these two tumours did not arise from the same stem cell but represent two different neoplastic growths.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekt / tema
00981103
00981104
101751

Ustanove
Institut "Ruđer Bošković", Zagreb,
Hrvatska akademija znanosti i umjetnosti

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE