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Solid-phase synthesis of palmitoylated and farnesylated lipopeptides employing the fluoride-labile PTMSEL linker (CROSBI ID 144401)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Lumbierres, M. ; Palomo, J. M. ; Kragol, Goran ; Waldmann, H. Solid-phase synthesis of palmitoylated and farnesylated lipopeptides employing the fluoride-labile PTMSEL linker // Tetrahedron letters, 47 (2006), 16; 2671-2674

Podaci o odgovornosti

Lumbierres, M. ; Palomo, J. M. ; Kragol, Goran ; Waldmann, H.

engleski

Solid-phase synthesis of palmitoylated and farnesylated lipopeptides employing the fluoride-labile PTMSEL linker

Acid- and base-labile S-palmitoylated and S-farnesylated lipopeptides can be synthesized in high overall yield employing the (2-phenyl-2-trimethylsilyl) ethyl (PTMSEL) linker for anchoring to and release under almost neutral conditions from the solid support.

Lipopeptides; Solid-phase synthesis; Linker groups; Ras protein

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Podaci o izdanju

47 (16)

2006.

2671-2674

objavljeno

0040-4039

Povezanost rada

Kemija

Indeksiranost