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Pregled bibliografske jedinice broj: 36043

Quantitative tissue carcinoembryonic antigen (T CEA) assay as a screening test for severe dysplasia in colorectal adenomas


Rosandić, Marija; Škegro, Mate; Paar, Vladimir; Paar, Dalibor; Šćukanec-Špoljar, Marija; Juričić, Marija; Vucelić, Boris; Rustemović, Nadan; Ostojić, Ranko; Ljubojević, Nikola
Quantitative tissue carcinoembryonic antigen (T CEA) assay as a screening test for severe dysplasia in colorectal adenomas // Acta Medica Austriaca, 26 (1999), 3; 89-92 (međunarodna recenzija, članak, znanstveni)


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Naslov
Quantitative tissue carcinoembryonic antigen (T CEA) assay as a screening test for severe dysplasia in colorectal adenomas

Autori
Rosandić, Marija ; Škegro, Mate ; Paar, Vladimir ; Paar, Dalibor ; Šćukanec-Špoljar, Marija ; Juričić, Marija ; Vucelić, Boris ; Rustemović, Nadan ; Ostojić, Ranko ; Ljubojević, Nikola

Izvornik
Acta Medica Austriaca (0303-8173) 26 (1999), 3; 89-92

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
carcinoembryonic antigen ; colorectal adenomas ; dysplasia ; tissue CEA concentration ; serum CEA concentration

Sažetak
Relationship between the serum (S CEA) and tissue (T CEA) carcinoembryonic antigen concentrations with regard to the degree of dysplasia in colorectal adenomas was investigated. Our study included 56 single or multiple colorectal adenomas in 46 patients. The measurements of T CEA concentrations were performed using the quantitative CEA-EIA method (Abbott) modified for wet tissue, obtained from heads of the adenomas. As a control point the mucosa near adenoma and the rectal mucosa were used. Our results suggest that the T CEA concentrations from the head of the adenoma demonstrate a highly significant difference between mild and severe dysplasia (P less than 0.001), between mild dysplasia and invasive adenocarcinoma (P less than 0.001) and a significant difference between mild and moderate dysplasia (P less than 0.05). On the other hand, the S CEA concentrations corresponding to these cases showed no such differences. In conclusion, we suggest the quantitative measurement of T CEA concentrations as a screening test for severe dysplasia in colorectal adenomas.

Izvorni jezik
Engleski

Znanstvena područja
Fizika



POVEZANOST RADA


Projekti:
214001
119211

Ustanove:
Prirodoslovno-matematički fakultet, Zagreb

Citiraj ovu publikaciju:

Rosandić, Marija; Škegro, Mate; Paar, Vladimir; Paar, Dalibor; Šćukanec-Špoljar, Marija; Juričić, Marija; Vucelić, Boris; Rustemović, Nadan; Ostojić, Ranko; Ljubojević, Nikola
Quantitative tissue carcinoembryonic antigen (T CEA) assay as a screening test for severe dysplasia in colorectal adenomas // Acta Medica Austriaca, 26 (1999), 3; 89-92 (međunarodna recenzija, članak, znanstveni)
Rosandić, M., Škegro, M., Paar, V., Paar, D., Šćukanec-Špoljar, M., Juričić, M., Vucelić, B., Rustemović, N., Ostojić, R. & Ljubojević, N. (1999) Quantitative tissue carcinoembryonic antigen (T CEA) assay as a screening test for severe dysplasia in colorectal adenomas. Acta Medica Austriaca, 26 (3), 89-92.
@article{article, year = {1999}, pages = {89-92}, keywords = {carcinoembryonic antigen, colorectal adenomas, dysplasia, tissue CEA concentration, serum CEA concentration}, journal = {Acta Medica Austriaca}, volume = {26}, number = {3}, issn = {0303-8173}, title = {Quantitative tissue carcinoembryonic antigen (T CEA) assay as a screening test for severe dysplasia in colorectal adenomas}, keyword = {carcinoembryonic antigen, colorectal adenomas, dysplasia, tissue CEA concentration, serum CEA concentration} }
@article{article, year = {1999}, pages = {89-92}, keywords = {carcinoembryonic antigen, colorectal adenomas, dysplasia, tissue CEA concentration, serum CEA concentration}, journal = {Acta Medica Austriaca}, volume = {26}, number = {3}, issn = {0303-8173}, title = {Quantitative tissue carcinoembryonic antigen (T CEA) assay as a screening test for severe dysplasia in colorectal adenomas}, keyword = {carcinoembryonic antigen, colorectal adenomas, dysplasia, tissue CEA concentration, serum CEA concentration} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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