engleski

Nitroxoline Mannich Bases-Relationship between Chromatographic RM values, Wiener's Numbers and Antibacterial Activities

A series of quinoline compounds, mostly 8-hydroxyauinoline (oxine) derivates were prepared and tested in vitro for their antibacterial activities. An attempt was made to determine Chromatographic RM parameter and to calculate Wiener's Numbers W(G) in order to find possible correlation of these parameters with bacteriostatic activities of the studied compounds.

Nitroxoline Mannich Bases ; Chromatographic RM value ; Wiener Number

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