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The role of viruses in reproduction and aneuploidy


Čulić, Vida; Mijaljica, Goran; Mišković, Silvana; Žegarac, Žana; Glavina Durdov, Merica; Čulić, Srđana; Primorac, Dragan
The role of viruses in reproduction and aneuploidy // European Human Genetics Conference 2005
Prag, Češka, 2005. (poster, međunarodna recenzija, sažetak, znanstveni)


Naslov
The role of viruses in reproduction and aneuploidy

Autori
Čulić, Vida ; Mijaljica, Goran ; Mišković, Silvana ; Žegarac, Žana ; Glavina Durdov, Merica ; Čulić, Srđana ; Primorac, Dragan

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
European Human Genetics Conference 2005

Mjesto i datum
Prag, Češka, 07-10.05.2005.

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Viruses; reproduction; aneuploidy

Sažetak
Abnormal centrosome duplication is tightly linked to aneuploidy. Spontaneus abortions appear with incidence of 12-15% in population. In spontaneous abortions there are 25-60% of chromosome abnormalities, and in most cases there are triploidies, tetraploides and polyploides. A retrospective analysis was done over 500 couples with one or more spontaneous abortion and 296 parafin embeded samples werw found. 41 placentas was analysed by flow: 66% diploid and 34% aneuploid. 30% had IgM or/and IgG for EBV and 4% for CMV. HPV positive diploid paraffin embedded sample from one couple with three consecutive spontaneous abortions was found.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



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