engleski

Sheep-associated malignant catarrhal fever : a case report

On a farm in north-west Croatia, where 17 diary cows and 2 heifers shared stables and meadows with dozen sheep, one of the heifers developed symptoms reminiscent of SA-MCF. Symptoms included anorexia, high fever, profuse catarrhal discharge from the eyes and nares, bilateral cornea opacity, necrosis of muzzle and erosions of the bucal epithelium. Ten days following onset of the disease neurological symptoms occurred. Animal died within 14 days. At the autopsy sharply demarcated erosions on the mucosal surfaces including tongue, oral mucosa, oesophagus, abomasum, jejunum, colon, caecum and urinary bladder were found. Histopathology revealed significant perivascular and intramural arterial infiltrations with mononuclear cells, mostly lymphocytes. Fluorogenic real-time PCR amplification specific for OvHV-2 was performed and OvHV-2 DNA was detected in brain, cerebellum, spleen and lymph nodes tissue samples. For the first time in Croatia OvHV-2 was identified and quantified as a causative agent of SA-MCF.

malignant catarrhal fever; ovine herpesvirus 2

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