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Pregled bibliografske jedinice broj: 346899

Population study at fifteen short tandem repeat loci in the representative sample of Bosnia and Herzegovina residents - contemporary data


Marjanović, Damir; Durmic-Pasic, Adaleta; Pjanic, N; Bakal, Narcisa; Kovačević, Lejla; Škaro, Vedrana; Projić, Petar; Haverić, Sanin; Bajrović, Kasim; Hadžiselimović, Rifat et al.
Population study at fifteen short tandem repeat loci in the representative sample of Bosnia and Herzegovina residents - contemporary data // European Journal of Human Genetics
Nica, Francuska: Nature Publishing Group, 2007. str. 305-305 (poster, međunarodna recenzija, sažetak, znanstveni)


Naslov
Population study at fifteen short tandem repeat loci in the representative sample of Bosnia and Herzegovina residents - contemporary data

Autori
Marjanović, Damir ; Durmic-Pasic, Adaleta ; Pjanic, N ; Bakal, Narcisa ; Kovačević, Lejla ; Škaro, Vedrana ; Projić, Petar ; Haverić, Sanin ; Bajrović, Kasim ; Hadžiselimović, Rifat ; Primorac, Dragan ; Pojskić Naris

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
European Journal of Human Genetics / - : Nature Publishing Group, 2007, 305-305

Skup
European Human Genetics Conference

Mjesto i datum
Nica, Francuska, 16-19. 06. 2007

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
STR loci; renewed data; Bosnia & Herzegovina

Sažetak
In our previous population studies of B&H human population, we used 17 autosomal and 12 Y-chromosomal STR loci, as well as 28 NRY bi-allelic markers to generate referent database. Wishing to test our database in order to obtain specific results in various DNA analysis, we have decided to analysis additional individuals, firstly at fifteen autosomal STR loci (D3S1358, TH01, D21S11, D18S51, Penta E, D5S818, D13S317, D7S820, D16S539, CSF1PO, Penta D, vWA, D8S1179, TPOX, FGA). Therefore, we have tested additional group of 100 unrelated healthy individuals born in B&H. Qiagen DnaeasyTM Tissue Kit was used for DNA extraction from buccal swabs and bloodstains and PowerPlex 16® ; ; System for amplification and detection. The total volume of PCR reaction was 5μ l and PCR amplifications were carried out in PE GeneAmp PCR System Thermal Cycler. Electrophoresis of the amplification products was preformed on an ABI PRISM 310 genetic analyzer. The raw data were compiled and analyzed using Genemapper® ; ; v3.2. Deviation from Hardy-Weinberg equilibrium, observed and expected heterozygosity, power of discrimination and power of exclusion were calculated. Statistical differences between the new set of data and the data at same loci published earlier (based on 100 tested individuals) indicated the advantage of using recently obtained frequencies, especially as it pertains to the forensic-genetic statistical analysis. In addition, we compared B&H data with the data obtained from geographically closer European populations. The results of this study will be used as guidelines in additional improving of investigation of recent B&H human populations, initiated in our previous studies.

Izvorni jezik
Engleski

Znanstvena područja
Biologija



POVEZANOST RADA


Projekt / tema
309-1300855-2738 - Razvoj sustava za DNA analizu arheoloških koštanih uzoraka (Damir Marjanović, )

Ustanove
Institut za antropologiju

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE