Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 346772

Impact of inflammatory cells activation on nasal hyperreactive response to distilled water nasal provocation


Zurak, Krešo; Bukovec, Željka; Anzić, Srdjan Ante; Baudoin, Tomislav; Kalogjera, Livije
Impact of inflammatory cells activation on nasal hyperreactive response to distilled water nasal provocation // Acta clinica Croatica, 46 (2007), 151-156 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 346772 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Impact of inflammatory cells activation on nasal hyperreactive response to distilled water nasal provocation

Autori
Zurak, Krešo ; Bukovec, Željka ; Anzić, Srdjan Ante ; Baudoin, Tomislav ; Kalogjera, Livije

Izvornik
Acta clinica Croatica (0353-9466) 46 (2007); 151-156

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
nasal hyperreactivity; inflammatory cells activity; ECP-eosinophil cationic potein; TRY-tryptase MPO-myeloperoxidase; nasal provocation; nasal lavage; active anterior rhinomanometry

Sažetak
The purpose of the study was to compare hyperreactive response to nasal distilled water provocation in the patients with allergic and non-allergic hyperreactive rhinitis and to correlate the severity of hyperreactivity with inflammatory cells activation. Cellular activity measured by the concentrations of cellular activation markers in nasal lavage prior to provocation, eosinophil cationic protein (ECP) for eosinophil granulocytes, myeloperoxidase (MPO) for neutrophilic granulocytes and tryptase for mast cells. The study was conducted in a group of 78 patients with nasal hyperreactivity according to patients history, 48 patients with perennial or seasonal allergic rhinitis and 30 patients with NINAR were included. Prior to provocation basal nasal airway resistance was measured by active anterior rhinomanometry, and nasal lavage with 5 ccm of saline was taken. Provocation was applied by inhalation of 10 ccm of distilled water during 10 minutes. Patients were divided in groups according to increase in NAR (no response, mild to moderate or severe response. In the whole group the provocation has induced a significant increase in nasal resistance on the better patent side prior to provocation (p<0, 005). The only significant difference detected between allergic and non-allergic patients was the tryptase concentration in nasal lavage, which was significantly higher in the allergic patients. No correlation was found between any of cellular markers and level of nasal hyperreactivity. The correlation between ECP and MPO in nasal lavage was significant. As no correlation between inflammatory cells activation and hyperreactivity was found, neural reflexes, besides inflammation, are probably involved in regulation of hyperreactive response.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
065-0650235-0145 - Istraživanje međuodnosa alergije i infekcije u rinosinuitisu i nosnoj polipozi (Kalogjera, Livije, MZOS ) ( POIROT)
108-0650235-0177 - Istraživanje kroničnog rinosinuitisa i njegova komorbiditeta (Baudoin, Tomislav, MZOS ) ( POIROT)

Ustanove:
Stomatološki fakultet, Zagreb,
Medicinski fakultet, Zagreb


Citiraj ovu publikaciju

Zurak, Krešo; Bukovec, Željka; Anzić, Srdjan Ante; Baudoin, Tomislav; Kalogjera, Livije
Impact of inflammatory cells activation on nasal hyperreactive response to distilled water nasal provocation // Acta clinica Croatica, 46 (2007), 151-156 (međunarodna recenzija, članak, znanstveni)
Zurak, K., Bukovec, Ž., Anzić, S., Baudoin, T. & Kalogjera, L. (2007) Impact of inflammatory cells activation on nasal hyperreactive response to distilled water nasal provocation. Acta clinica Croatica, 46, 151-156.
@article{article, year = {2007}, pages = {151-156}, keywords = {nasal hyperreactivity, inflammatory cells activity, ECP-eosinophil cationic potein, TRY-tryptase MPO-myeloperoxidase, nasal provocation, nasal lavage, active anterior rhinomanometry}, journal = {Acta clinica Croatica}, volume = {46}, issn = {0353-9466}, title = {Impact of inflammatory cells activation on nasal hyperreactive response to distilled water nasal provocation}, keyword = {nasal hyperreactivity, inflammatory cells activity, ECP-eosinophil cationic potein, TRY-tryptase MPO-myeloperoxidase, nasal provocation, nasal lavage, active anterior rhinomanometry} }
@article{article, year = {2007}, pages = {151-156}, keywords = {nasal hyperreactivity, inflammatory cells activity, ECP-eosinophil cationic potein, TRY-tryptase MPO-myeloperoxidase, nasal provocation, nasal lavage, active anterior rhinomanometry}, journal = {Acta clinica Croatica}, volume = {46}, issn = {0353-9466}, title = {Impact of inflammatory cells activation on nasal hyperreactive response to distilled water nasal provocation}, keyword = {nasal hyperreactivity, inflammatory cells activity, ECP-eosinophil cationic potein, TRY-tryptase MPO-myeloperoxidase, nasal provocation, nasal lavage, active anterior rhinomanometry} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
  • Scopus


Uključenost u ostale bibliografske baze podataka:


  • EMBASE (Excerpta Medica)





Contrast
Increase Font
Decrease Font
Dyslexic Font