engleski

Influence of cardiac surgery on the outcome of patients with infective endocarditis complicated with ischemic stroke

Background: Stroke occurs in about 20% of patients with IE. In a previous study we showed that cardiac surgery (CS) during acute episode of IE decreases intrahospital mortality in patients complicated with stroke. The differences in the outcome of patients between ischemic and hemorrhagic shock were not elucidated. The aim of the study was to assess the influence of cardiac surgery on patients' outcome in a group of patients with IE complicated with ischemic stroke. Methods and Results: From January 1, 2000 and August 31 2005, 2760 cases of definite IE were included by 61 centers in 28 countries. Each center utilized a standard case report form. Stroke was defined as an acute neurological deficit of vascular etiology lasting >24 hours. Stroke was characterized as ischemic or hemorrhagic using neuroimaging results. Ischemic stroke was observed in 318 (11.5%) of 2760 patients with IE. Mean age of patients with stroke was 57.8+-16.7 years. Male gender dominated (209 patients, 65.7%). Main characteristics of IE in these patients are presented on tables 1. and 2.

endocarditis; stroke; surgery

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