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Pregled bibliografske jedinice broj: 346229

Results of the Determination of Serum Markers in Patients with Malignant Melanoma


Lugović, Liborija; Šitum, Mirna; Buljan, Marija; Poduje, Sanja; Šebetić, Klaudija
Results of the Determination of Serum Markers in Patients with Malignant Melanoma // Collegium Antropologicum, 31 (2007), Supplement 1; 7-13 (podatak o recenziji nije dostupan, članak, ostalo)


Naslov
Results of the Determination of Serum Markers in Patients with Malignant Melanoma

Autori
Lugović, Liborija ; Šitum, Mirna ; Buljan, Marija ; Poduje, Sanja ; Šebetić, Klaudija

Izvornik
Collegium Antropologicum (0350-6134) 31 (2007), Supplement 1; 7-13

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo

Ključne riječi
Malignant melanoma; markers; lactate dehydrogenase (LDH); protein S-100; melanoma-inhibiting activity (MIA); tyrosinase

Sažetak
Although there is no routine procedure for determination of serum markers in patients with malignant melanoma (MM), some markers are being studied as potentially useful prognostic tools. Serum lactate dehydrogenase (LDH), protein S- 100B, melanoma-inhibiting activity (MIA) and tyrosinase may correlate with melanoma progression. In this study, the results of determination of S100 protein, LDH, MIA and tyrosinase in the serum of 50 patients with MM (stages I-IV) were determined. The increased values of MIA were found in 26% patients in stage I, while in 50% patients in stage IV. Increased S-100 protein was found in 13% patients in stage I while in 50% patients in stage IV. The increased values of LDH were found in 26% patients in stage I, while in 25% patients in stage IV. The positive serum tyrosinase was noticed in 17.3% patients in stage II, while in 25% patients in stage IV. The obtained results have revealed no significant differences between the groups in higher and lower stages of the disease, indicating that blood markers are not reliable prognostic factors for MM progression.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
134-1342428-2420 - Psihološki status bolesnika s različitim dermatozama i zloćudnim bolestima kože (Mirna Šitum, )

Ustanove
KBC "Sestre Milosrdnice"

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE