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Pregled bibliografske jedinice broj: 342318

Serum gangliosides in patients with brain tumors


Radić, Borislav; Vukelić, Željka; Kalanj Bognar, Svjetlana
Serum gangliosides in patients with brain tumors // Collegium Antropologicum, 32 (2008), suppl 1; 171-175 (međunarodna recenzija, članak, znanstveni)


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Naslov
Serum gangliosides in patients with brain tumors

Autori
Radić, Borislav ; Vukelić, Željka ; Kalanj Bognar, Svjetlana

Izvornik
Collegium Antropologicum (0350-6134) 32 (2008), Suppl 1; 171-175

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
serum; gangliosides; brain tumors

Sažetak
In order to determine possible differences in serum gangliosides content and composition before and after surgical removal of tumor, gangliosides isolated from preoperative and postoperative sera of patients with brain tumors were analyzed. Serum samples were collected from patients with glioblastoma, meningioma, acoustic neurinoma, haemangioma, oligodendroglioma and astrocytoma, one week before and one week after surgical removal of the tumor. Serum gangliosides were qualitatively and quantitatively analyzed by high performance thin layer chromatography and laser densitometry. Results showed changes of total gangliosides concentrations in analyzed postoperative sera comparing to preoperative sera. There was not a significant difference in ganglioside pattern of preoperative vs. preoperative sera. However, a postoperative decreased proportion of ganglioside GD3 was observed in sera derived from patients with complete tumor removal. The results of this study indicate that comparative quantitative and compositional analysis of both preoperative and postoperative serum gangliosides may provide useful information concerning tumor progression, surgical success and prognosis.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekt / tema
108-1081870-1877 - Uloga membranskih lipida u moždanom razvitku, starenju i neurodegeneraciji (Kalanj-Bognar, Svjetlana, MZOS - )
108-1081870-2415 - Strukturno-funkcionalna glikolipidomika moždanog razvitka i maligne alteracije (Vukelić, Željka, MZOS - )

Ustanove
Medicinski fakultet, Zagreb

Citiraj ovu publikaciju

Radić, Borislav; Vukelić, Željka; Kalanj Bognar, Svjetlana
Serum gangliosides in patients with brain tumors // Collegium Antropologicum, 32 (2008), suppl 1; 171-175 (međunarodna recenzija, članak, znanstveni)
Radić, B., Vukelić, Ž. & Kalanj Bognar, S. (2008) Serum gangliosides in patients with brain tumors. Collegium Antropologicum, 32 (suppl 1), 171-175.
@article{article, year = {2008}, pages = {171-175}, keywords = {serum, gangliosides, brain tumors}, journal = {Collegium Antropologicum}, volume = {32}, number = {suppl 1}, issn = {0350-6134}, title = {Serum gangliosides in patients with brain tumors}, keyword = {serum, gangliosides, brain tumors} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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