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Pregled bibliografske jedinice broj: 341995

Possible prognostic significance of p53 and Ki 67 in inverted sinonasal papilloma


Bura, Miljenko; Seiwerth, Sven; Vladika, Ivan; Perović, Darko; Nagy, Paul; Ćorić, Marijana; Bijelić, Lana; Krajina, Zdenko; Žižić Mitrečić, Marica
Possible prognostic significance of p53 and Ki 67 in inverted sinonasal papilloma // Collegium antropologicum, 31 (2007), 2; 545-549 (međunarodna recenzija, članak, znanstveni)


Naslov
Possible prognostic significance of p53 and Ki 67 in inverted sinonasal papilloma

Autori
Bura, Miljenko ; Seiwerth, Sven ; Vladika, Ivan ; Perović, Darko ; Nagy, Paul ; Ćorić, Marijana ; Bijelić, Lana ; Krajina, Zdenko ; Žižić Mitrečić, Marica

Izvornik
Collegium antropologicum (0350-6134) 31 (2007), 2; 545-549

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Inverted papilloma; sinus

Sažetak
The aim of this study is to test the possible prognostic significance of p53 and Ki67 expression in inverted papilloma of the lateral nasal wall and adjacent sinuses regarding their malignant potential and recurrence. 49 biopsies of the lateral nasal wall and adjacent sinuses obtained from 41 patients from three hospitals were investigated. Immunohistochemically demonstrated p53 and Ki67 expression was measured and statistically evaluated. p53 immunoreactivity was demonstrated in most of papillomas with carcinomas but only in two benign papillomas, while Ki67 demonstrated stronger immunoreactivity in carcinomas and surrounding epithelium. Immunohistochemical staining of inverted sinonasal papillomas for p53 and Ki67 can give useful information concerning the existence of synchronous carcinoma and, in case of high Ki67, a hint toward possible recurrence.

Izvorni jezik
Engleski



POVEZANOST RADA


Projekt / tema
108-0000000-0051 - Molekularna osnova raka štitnjače-kriteriji u terapiji diferenciranih karcinoma (Miljenko Bura, )

Ustanove
Medicinski fakultet, Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE