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Are serum lipids measured on stroke admission prognostic?


Šimundić, Ana-Maria; Nikolac, Nora; Topić, Elizabeta; Bašić-Kes, Vanja; Demarin, Vida
Are serum lipids measured on stroke admission prognostic? // Clinical Chemistry and Laboratory Medicine, 46 (2008), 8; 1163-1167 doi:10.1515/CCLM.2008.233 (međunarodna recenzija, kratko priopcenje, znanstveni)


Naslov
Are serum lipids measured on stroke admission prognostic?

Autori
Šimundić, Ana-Maria ; Nikolac, Nora ; Topić, Elizabeta ; Bašić-Kes, Vanja ; Demarin, Vida

Izvornik
Clinical Chemistry and Laboratory Medicine (1434-6621) 46 (2008), 8; 1163-1167

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kratko priopcenje, znanstveni

Ključne riječi
Cerebrovascular accident; cholesterol; lipid profile; prognosis; triglycerides

Sažetak
Background: It has been hypothesized that serum lipids measured in early period of stroke are predictive of stroke severity and outcome. The optimal time for lipid measurement is not established. We explored whether lipid profile assessed within the first 24 hours after stroke onset: (i) differs from stroke-free individuals ; (ii) differs between stroke subtypes and (iii) is predictive of stroke severity and outcome. Methods: We prospectively enrolled 70 acute ischemic stroke patients who presented to the Stroke Unit within the 24 hours of the onset of stroke symptoms, and 68 stroke-free controls. Results: Triglycerides (P<0.001) and HDL cholesterol (P<0.001) were significantly lower in patients, than in controls. HDL cholesterol was different across stroke subtypes classified according to TOAST scale (P=0.035). Patients with more severe stroke had higher serum triglycerides (OR 2.755 ; P=0.030). Conclusions: Serum triglycerides might serve as a prognostic marker in acute stroke patient.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
134-1340036-0033 - Uloga genetskih markera u razvoju cerebralne aterosklerotske bolesti (Vida Demarin, )
134-1340227-0200 - Upala i udio farmakogenetike u razvoju i ishodu akutnih i kroničnih bolesti (Ana-Maria Šimundić, )

Ustanove
KBC "Sestre Milosrdnice"

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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