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The assessment of ovarian tumor angiogenesis: what does three-dimensional power Doppler add? (CROSBI ID 84999)

Prilog u časopisu | stručni rad

Kurjak, Asim ; Kupešić, Sanja ; Breyer, Branko ; Šparac, Vladimir ; Jukić, Stanko The assessment of ovarian tumor angiogenesis: what does three-dimensional power Doppler add? // Ultrasound in obstetrics & gynecology, 12 (1998), 2; 136-146-x

Podaci o odgovornosti

Kurjak, Asim ; Kupešić, Sanja ; Breyer, Branko ; Šparac, Vladimir ; Jukić, Stanko

engleski

The assessment of ovarian tumor angiogenesis: what does three-dimensional power Doppler add?

It has been known for over 25 years that the development of new blood vessels is necessary to sustain the growth, invasion and metastasis of tumors. Angiogenesis is crucial for sustaining tumor growth, as it allows oxygenation and nutritient perfusion of the tumor as well as removal of waste products. Moreover, increased angiogensesis coincides with increased tumor cell entry into the circulation, and thus facilitates metastasis. Cancer cells activate the quiescent vasculature to produce new blood vessels via an 'angiogenetic switch', often during the premalignant stages of tumor development. Data suggestinf that control ofangiogenesis is separate from control of canncer cell proliferation raise the possibility that drugs inhibiting angiogenesis could offer a treatment that is complementary to traditional chemotherapy, which directly targets tumor cells. This exciting possibility has stimulated current research on tumor angiogenesis.

ultrasound; three dimensional imaging; fractal geometry; angiogenesis; tumor angiogenesis; blood vessel branching descriptors

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Podaci o izdanju

12 (2)

1998.

136-146-x

objavljeno

0960-7692

Povezanost rada

Javno zdravstvo i zdravstvena zaštita

Indeksiranost