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Ewing's sarcoma: a retrospective study

In most Ewing's sarcoma there is expression of MIC/CD99 and it is also associated with t(11 ; 22) translocation yielding a fusion between the EWS and FLI1 genes yielding the most common among chimeric genes found in Ewing's sarcoma. Since 1998, immunohistochemical verification of ES/PNET diagnosis, using CD99, is routinely performed at our Institute. Since end 2003., molecular methods (RT-PCR for EWS/FLI1) were introduced. In 2003, an algorithm was adopted including molecular analysis for residual disease and early recurrence detection.

Ewing's sarcoma; retrospective study

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