engleski

Features of uremic neuropathy in long-term dialysis

In order to assess the influence of long term hemodialysis on progression of uraemic neuropathy (UN), 16 different electroneurographic (ENG) parameters on. 158 dialysis patients were performed. The ENG parameters mere compared in three groups of patients of different dialysis age. Group I: high dialysis age (HDA) comprising of 31 patients being more than 10 years on dialysis ; Group II: intermediate dialysis age (IDA) comprising of 53 patients between 5 and 10 years on ND and group III: low, dialysis age (LDA) comprising of 74 patients being less than 5 years on dialysis. The influence of sex and age teas also analyzed. All sixteen tested parameters were altered in uremic patients when compared to 140 healthy controls (p < 0.01). HDA pts compared to LDA pts and the older group versus the younger had II and 9 out of 16 ENG parameters significantly worsened, respectivelly (p < 0.01). The most profound and reproducible lesion was in prolongation of evoked potential of tibialis posterior and peroneus nerve (FWt, HWt, FWp). HDA, especially after 10 yrs and the age but not the sex is clearly associated with a further progression of UN. However, for unknown, reasons, the progression. of UN in dialyzed patients is not followed by a parallel worsening of clinical symptoms (p > 0.05).

uremic neuropathy; long-term dialisys; electroneurography

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