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Pregled bibliografske jedinice broj: 335545

Assessment of Crohn's disease activity by doppler ultrasound of superior mesenteric artery and mural arteries in thickened bowel wall: cross-sectional study


Sjekavica, Ivica; Barbarić-Babić, Vinka; Krznarić, Željko; Molnar, Melita; Čuković-Čavka, Silvija; Štern-Padovan, Ranka
Assessment of Crohn's disease activity by doppler ultrasound of superior mesenteric artery and mural arteries in thickened bowel wall: cross-sectional study // Croatian Medical Journal, 48 (2007), 6; 822-830 doi:10.3325/cmj.2007.6.822. (međunarodna recenzija, članak, znanstveni)


Naslov
Assessment of Crohn's disease activity by doppler ultrasound of superior mesenteric artery and mural arteries in thickened bowel wall: cross-sectional study

Autori
Sjekavica, Ivica ; Barbarić-Babić, Vinka ; Krznarić, Željko ; Molnar, Melita ; Čuković-Čavka, Silvija ; Štern-Padovan, Ranka

Izvornik
Croatian Medical Journal (0353-9504) 48 (2007), 6; 822-830

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Chron disease; doppler ultrasound

Sažetak
Aim: To define sensitive and reliable Doppler parameters for measurements in the superior mesenteric artery and mural arteries of affected bowel loops used in the assessment of Crohn disease activity. Methods: We performed cross-sectional study at a tertiary care setting in Zagreb, Croatia, between January 2001 and March 2005. We measured arterial flow in the superior mesenteric artery and affected bowel wall in 138 patients with Crohn disease (74 with active, 64 with inactive disease) and 67 healthy volunteers. The disease activity was determined by the clinical examination, Crohn disease activity index, and standard laboratory tests. Superior mesenteric artery color and pulsed Doppler parameters were peak systolic velocity, end-diastolic velocity, resistance index, mean velocity flow, cross-sectional area, and flow volume. When gut mural vessels were identified, we performed spectral analysis of mural arteries by pulsed Doppler, with a measurement of resistance index. Results: The measurements in the superior mesenteric artery showed statistically and clinically significant difference in flow volume in active group, compared with inactive and control groups (C+/-Q=564+/-263 mL/min for active, 421+/-157 for inactive and 416+/-248 for control group). Affected bowel loops analysis showed significant difference between inactive and active Crohn disease group in wall thickness (3.1+/-1.4 vs 5.0+/-1.8 mm, P<0.001, Mann-Whitney test) while all participants from control group had thickness below 2mm. Intensity of color Doppler signals was different for all groups (P<0.001, chi(2) test) with the highest level of hyperemia in the active group. Resistance index measurements of mural arteries in bowel wall revealed differences between all three groups (0.61+/-0.05 in active group, 0.71+/-0.05 in the inactive group and 0.80+/-0.11 in the control group, P<0.001, Kruskal-Wallis test). CONCLUSION: Intensity of color Doppler signals and resistance index measurements of mural arteries in the thickened bowel wall can be used as quantitative diagnostic tool in the assessment of Crohn disease activity.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
108-1081870-1947 - Prikaz perinatalnih čimbenika značajnih za dugoročni neurorazvojni ishod (Snježana Škrablin-Kučić, )
108-1081872-1908 - Dijagnostika i liječenje limfoma (Igor Aurer, )
108-1081874-1917 - Upalne bolesti crijeva (Crohnova bolest i ulcerozni kolitis) (Boris Vucelić, )

Ustanove
Medicinski fakultet, Zagreb

Citiraj ovu publikaciju

Sjekavica, Ivica; Barbarić-Babić, Vinka; Krznarić, Željko; Molnar, Melita; Čuković-Čavka, Silvija; Štern-Padovan, Ranka
Assessment of Crohn's disease activity by doppler ultrasound of superior mesenteric artery and mural arteries in thickened bowel wall: cross-sectional study // Croatian Medical Journal, 48 (2007), 6; 822-830 doi:10.3325/cmj.2007.6.822. (međunarodna recenzija, članak, znanstveni)
Sjekavica, I., Barbarić-Babić, V., Krznarić, Ž., Molnar, M., Čuković-Čavka, S. & Štern-Padovan, R. (2007) Assessment of Crohn's disease activity by doppler ultrasound of superior mesenteric artery and mural arteries in thickened bowel wall: cross-sectional study. Croatian Medical Journal, 48 (6), 822-830 doi:10.3325/cmj.2007.6.822..
@article{article, year = {2007}, pages = {822-830}, DOI = {10.3325/cmj.2007.6.822.}, keywords = {Chron disease, doppler ultrasound}, journal = {Croatian Medical Journal}, doi = {10.3325/cmj.2007.6.822.}, volume = {48}, number = {6}, issn = {0353-9504}, title = {Assessment of Crohn's disease activity by doppler ultrasound of superior mesenteric artery and mural arteries in thickened bowel wall: cross-sectional study}, keyword = {Chron disease, doppler ultrasound} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • MEDLINE


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