engleski

Influence of the type and degree of LVH on the prevalence of ventricular arrhythmias in patients with hypertensive heart disease

We investigated the correlation between the type and degree of left ventricular hypertrophy (LVH) and the prevalence of ventricular arrhythmias (VA) in hypertensive patients with LVH. A total of 192 patients (87 men and 105 women)without coronary disease were divided into three groups according to type of LVH (concentric, eccentric and asymmetric)and three subgroups in relation to the degree of hypertrophy (mild, moderate and severe). In all subjects blood pressure was measured, electrocardiographic and echocardiographic data obtained and the prevalence of VA determined by Holter monitoring and bicycle ergometry. The most frequent LVH type was the concentric (63%), followed by eccentric (28%) and asymmetric (9%). Severe LVH was found in 10% of patients. Patients with eccentric LVH had significantly higher left ventricualar mass index then those with concentric LVH (p=0.011). Patients with asymmetric LVH presented no significant difference in relation to the concentric and accentric. Complex VA during Holter monitoring was identified in over 40% of patients. There was no statistically sigificant difference between groups in frequency of simple (p=0.757) and complex (p=0.657, p=0.819, p=0.617, for polytopic, pairs and ventricular tachycardia, respectively) VA. Increased prevalence od VA was found for the moderate and severe degree in all types. In the concentric type the difference was statistically significant for simple VA (p=0.042). In conclusion, there was no correlation between types of LVH and prevalence of VA. The severity of hypertrophy slightly contributes to a greater prevalence of the same. Asymmetric hypertrophy carries no increased risk.

left ventricular hypertrophy; cardiac arrhythmias; hypertension; heart disease

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