Thymus alterations related to intravenous drug abuse (CROSBI ID 138440)
Prilog u časopisu | stručni rad | međunarodna recenzija
Podaci o odgovornosti
Glavina-Durdov, Merica ; Definis-Gojanović, Marija
engleski
Thymus alterations related to intravenous drug abuse
It has been noticed on forensic material that Hassall's corpuscles of the thymus are more often calcified in intravenous drug abusers than in healthy persons. Thymuses of 15 intravenous heroin addicts were histologically examined and compared with thymuses of 15 healthy persons. Acute bleeding and dystrophic calcification in the thymocyte's parenchyma were more common among intravenous drug abusers (p = .005 and p = .001, respectively). The degree of physiologic involution measured by fatty replacement and the clarity of border between cortex and medulla was equal. No significant diversity was found in the features of Hassall's bodies. Our study emphasizes the necessity for a defined criteria of morphologic changes in the thymus that could be expected in intravenous drug abusers. In that way it would be possible to complete the forensic findings as well as to examine immunologic system alterations of that risk population.
thymus alterations; intravenuous drug abuse
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Podaci o izdanju
20 (2)
1999.
150-153
objavljeno
0195-7910
1533-404X
10.1097/00000433-199906000-00009
Povezanost rada
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita