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Preparation and structure of 2-ferrocenyl-1-phenylethyl acetate

Optically active ferrocene derivatives are widely used as synthetic building blocks for numerous natural products, pharmaceuticals and fine chemicals. The title compound (1) was prepared as a part of research on biocatalyzed acylations of secondary omega-ferrocenylalkanols. The purpose of this work was to study the effect of substituents on the stability of beta-carbocation in SN-transformations of Fc-substrates [1, 2]. The structure of compound 1 was confirmed by IR, NMR-spectroscopy and X-ray crystal structure analysis (Fig. 1). The molecules of 1 are linked by one weak C-H• • • O hydrogen bond, thus generating infinite chains parallel to the c axis. This hydrogen bond is reinforced by one C-H• • • p interaction, so producing two-dimensional network (Fig. 2).

ferrocene; beta-carbocation; X-ray crystal structure analysis

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