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A novel pyrene-guanidiniocarbonyl-pyrrole cation efficiently differentiates between ds-DNA and ds-RNA by two independent, sensitive spectroscopic methods


Hernandez-Folgado, Laura; Schmuck, Carsten; Tomić, Sanja; Piantanida, Ivo
A novel pyrene-guanidiniocarbonyl-pyrrole cation efficiently differentiates between ds-DNA and ds-RNA by two independent, sensitive spectroscopic methods // Bioorganic & Medicinal Chemistry Letters, 18 (2008), 2977-2981 doi:10.1016/j.bmcl.2008.03.060 (međunarodna recenzija, članak, znanstveni)


Naslov
A novel pyrene-guanidiniocarbonyl-pyrrole cation efficiently differentiates between ds-DNA and ds-RNA by two independent, sensitive spectroscopic methods

Autori
Hernandez-Folgado, Laura ; Schmuck, Carsten ; Tomić, Sanja ; Piantanida, Ivo

Izvornik
Bioorganic & Medicinal Chemistry Letters (0960-894X) 18 (2008); 2977-2981

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
guanidinium; pyrene; pyrrole; ds-DNA; ds-RNA.

Sažetak
At micromolar concentrations and equimolar conditions in respect to basepairs, a novel pyrene-guanidiniocarbonyl-pyrrole cation 1 exhibited a strong ICD signal at about  = 300 nm specifically upon the interaction with ds-DNA, while under the same conditions a new fluorescence maximum at  = 480 nm appeared exclusively upon the addition of ds-RNA.

Izvorni jezik
Engleski

Znanstvena područja
Fizika, Kemija



POVEZANOST RADA


Projekt / tema
098-0982914-2918 - Dizajn, sinteza i ispitivanje interakcija malih molekula s DNA, RNA i proteinima (Ivo Piantanida, )
098-1191344-2860 - Proučavanje biomakromolekula računalnim metodama i razvoj novih algoritama (Sanja Tomić, )

Ustanove
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Ivo Piantanida (autor)

Avatar Url Sanja Tomić (autor)

Citiraj ovu publikaciju

Hernandez-Folgado, Laura; Schmuck, Carsten; Tomić, Sanja; Piantanida, Ivo
A novel pyrene-guanidiniocarbonyl-pyrrole cation efficiently differentiates between ds-DNA and ds-RNA by two independent, sensitive spectroscopic methods // Bioorganic & Medicinal Chemistry Letters, 18 (2008), 2977-2981 doi:10.1016/j.bmcl.2008.03.060 (međunarodna recenzija, članak, znanstveni)
Hernandez-Folgado, L., Schmuck, C., Tomić, S. & Piantanida, I. (2008) A novel pyrene-guanidiniocarbonyl-pyrrole cation efficiently differentiates between ds-DNA and ds-RNA by two independent, sensitive spectroscopic methods. Bioorganic & Medicinal Chemistry Letters, 18, 2977-2981 doi:10.1016/j.bmcl.2008.03.060.
@article{article, year = {2008}, pages = {2977-2981}, DOI = {10.1016/j.bmcl.2008.03.060}, keywords = {guanidinium, pyrene, pyrrole, ds-DNA, ds-RNA.}, journal = {Bioorganic and Medicinal Chemistry Letters}, doi = {10.1016/j.bmcl.2008.03.060}, volume = {18}, issn = {0960-894X}, title = {A novel pyrene-guanidiniocarbonyl-pyrrole cation efficiently differentiates between ds-DNA and ds-RNA by two independent, sensitive spectroscopic methods}, keyword = {guanidinium, pyrene, pyrrole, ds-DNA, ds-RNA.} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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