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Generation of measles virus subgenomic RNA in human diploid and Vero cell culture and their presence in attenuated live measles virus vaccine


Košutić, Tanja; Forčić, Dubravko; Markotić, Alemka; Mažuran, Renata
Generation of measles virus subgenomic RNA in human diploid and Vero cell culture and their presence in attenuated live measles virus vaccine // Periodicum biologorum / Branko Vitale (ur.).
Zagreb: Hrvatsko prirodoslovno društvo, 1997. str. 41-41 (poster, međunarodna recenzija, sažetak, znanstveni)


Naslov
Generation of measles virus subgenomic RNA in human diploid and Vero cell culture and their presence in attenuated live measles virus vaccine

Autori
Košutić, Tanja ; Forčić, Dubravko ; Markotić, Alemka ; Mažuran, Renata

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Periodicum biologorum / Branko Vitale - Zagreb : Hrvatsko prirodoslovno društvo, 1997, 41-41

ISBN
0031-5362

Skup
Annual Meeting of the Croatian Immunological Society

Mjesto i datum
Zagreb, 06-07.11.1997

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Measles; genome; RNA

Sažetak
Almost all negative stranded RNA viruses cause the occurrence of the subgenomic RNA. Live measles virus vaccines are attenuated by several passages in different animal cell cultures. Repeated passages of undiluted virus stock can generate detectable subgenomic RNA, whose fequency is influenced by the virus strain, cell type and virus passage history. A systematic study was made to detect the different size of RNA in the attenuated live measles virus Edmonston-Zagreb vaccine.

Izvorni jezik
Engleski

Znanstvena područja
Farmacija



POVEZANOST RADA


Projekt / tema
021001

Ustanove
Imunološki zavod d.d.