engleski

Synthesis and structure of N-substituted (1-ferrocenylethyl)amine derivatives

N-Acetyl-(1-ferrocenylethyl)amine (8) was synthesized by N-acylation of (1-ferrocenylethyl)amine (7) in 84% yield. Reaction of N-acetyl-[1-(1'-bromo-ferrocenyl)ethyl]amine (4) (which was prepared by multistep sequence starting from bromoferrocene) with n-BuLi/ ClCOOEt gave 77% of N-acetyl-N-ethoxycarbonyl-(1-ferrocenylethyl)amine (6) instead of the expected ethyl 1'-[1-(acetamido)ethyl]ferrocene-1-carboxylate (5). Both structures were undoubtedly confirmed by (HR)MS, spectroscopy and single crystal X-ray structure analysis.

ferrocene ; amine ; lithiation ; ethoxycarbonylation ; structure analysis

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