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Pregled bibliografske jedinice broj: 322839

Synthesis and structural characterization of metallated bioconjugates: C-terminal labeling of amino acids with aminoferrocene


Jios, Jorge L.; Kirin, Srećko I.; Buceta, Norma N.; Weyhermüller, Thomas; Della Vedova, Carlos O.; Metzler-Nolte, Nils
Synthesis and structural characterization of metallated bioconjugates: C-terminal labeling of amino acids with aminoferrocene // Journal of Organometallic Chemistry, 692 (2007), 20; 4209-4214 (međunarodna recenzija, članak, znanstveni)


Naslov
Synthesis and structural characterization of metallated bioconjugates: C-terminal labeling of amino acids with aminoferrocene

Autori
Jios, Jorge L. ; Kirin, Srećko I. ; Buceta, Norma N. ; Weyhermüller, Thomas ; Della Vedova, Carlos O. ; Metzler-Nolte, Nils

Izvornik
Journal of Organometallic Chemistry (0022-328X) 692 (2007), 20; 4209-4214

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Amino acids; bioorganometallic chemistry; ferrocene; peptides; X-ray

Sažetak
Aminoferrocene, H2N– Fc, has been substituted to the C-terminus of six amino acids using the HBTU/HOBt coupling protocol. The synthesized bioconjugates Boc-Aaa-NH-Fc, Aaa = Gly (1), Leu (2), Phe (3), Val (4), Cys(Acm) (5), Tyr(tBu) (6) (Acm = acetamidomethyl, tBu = tert-butyl), have been characterized by 1H NMR, 13C NMR, EI-MS, EI-HRMS, UV and CD spectroscopies. In addition, a VT NMR study on 4 and the X-ray structure of 1 are presented.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Autor s matičnim brojem:
Srećko Kirin, (192540)

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus