hrvatski

Primjena lasera niske izlazne snage u liječenu kserostomije

Reduction in salivary secretion is known as xerostomia. Because of inadequate mechanical cleaning of the mouth and decrease in the levels of salivary antimicrobial proteins, it is accompanied with difficulties during speaking and food swallowing but also with higher susceptibility to oral infections, periodontal diseases and caries. It is well-known that low-level laser treatment (LLLT) can intensify cell metabolism. This led us to assume that its application on salivary glands could result in the improvement of salivation. Aims The aim of this study was to investigate whether it is possible to increase salivary flow rate in patient suffering from xerostomia by applying of LLLT to their salivary glands. The second aim was to ascertain if LLLT induces synthesis of secretory immunoglobulinA (sIgA) in salivary glands. Patients and methods The study included 18 patients diagnosed with xerostomia. Their major salivary glands were treated with low intensity laser BTL 2000 (energy density 1, 8 J/cm2, frequency 5, 2 Hz, output power 30 mW) on 10 occasions (five times weekly), every treatment lasting 16 minutes. Each parotid gland was exposed for 5 minutes, submandibular glands were exposed for 2 and sublingual for 1 minute per treatment. The whole unstimulated and stimulated saliva quantities were measured just before the first treatment, after the tenth treatment and thirty days following the last (tenth) treatment. In the samples of unstimulated saliva, using enzyme-linked immunosorbent assay, concentrations of sIgA were estimated and it’ s quantity in the time unit was calculated. Results The results of the LLLT of xerostomic patients’ major salivary glands indicate salivation improvement quantitatively and quantitatively, i.e. increase in the quantity of saliva and sIgA. Adverse side-effects were not observed. Conclusions This preliminary study proves the positive therapeutic effect of the LLLT on xerostomic patients’ major salivary glands. By applying of the LLLT, it is possible to stimulate them to produce more saliva with better antimicrobial characteristics and to facilitate the difficulties that are accompanied with xerostomia and eventually improve their quality of life. Further investigation is needed to ascertain if this simple, non-invasive method can be introduced in everyday clinical practice as a routine procedure for the treatment of xerostomia.

laser niske izlazne snage; suhoća usta; sIgA

nije evidentirano

engleski

Low-level Laser in the Treatment of Xerostomia

Reduction in salivary secretion is known as xerostomia. Because of inadequate mechanical cleaning of the mouth and decrease in the levels of salivary antimicrobial proteins, it is accompanied with difficulties during speaking and food swallowing but also with higher susceptibility to oral infections, periodontal diseases and caries. It is well-known that low-level laser treatment (LLLT) can intensify cell metabolism. This led us to assume that its application on salivary glands could result in the improvement of salivation. Aims The aim of this study was to investigate whether it is possible to increase salivary flow rate in patient suffering from xerostomia by applying of LLLT to their salivary glands. The second aim was to ascertain if LLLT induces synthesis of secretory immunoglobulinA (sIgA) in salivary glands. Patients and methods The study included 18 patients diagnosed with xerostomia. Their major salivary glands were treated with low intensity laser BTL 2000 (energy density 1, 8 J/cm2, frequency 5, 2 Hz, output power 30 mW) on 10 occasions (five times weekly), every treatment lasting 16 minutes. Each parotid gland was exposed for 5 minutes, submandibular glands were exposed for 2 and sublingual for 1 minute per treatment. The whole unstimulated and stimulated saliva quantities were measured just before the first treatment, after the tenth treatment and thirty days following the last (tenth) treatment. In the samples of unstimulated saliva, using enzyme-linked immunosorbent assay, concentrations of sIgA were estimated and it’ s quantity in the time unit was calculated. Results The results of the LLLT of xerostomic patients’ major salivary glands indicate salivation improvement quantitatively and quantitatively, i.e. increase in the quantity of saliva and sIgA. Adverse side-effects were not observed. Conclusions This preliminary study proves the positive therapeutic effect of the LLLT on xerostomic patients’ major salivary glands. By applying of the LLLT, it is possible to stimulate them to produce more saliva with better antimicrobial characteristics and to facilitate the difficulties that are accompanied with xerostomia and eventually improve their quality of life. Further investigation is needed to ascertain if this simple, non-invasive method can be introduced in everyday clinical practice as a routine procedure for the treatment of xerostomia.

low-level laser treatment; xerostomia; sIgA

nije evidentirano