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Serum-free culture of mammalian embryo does not restrict developmental potential for differentiation of skin appendages (CROSBI ID 84402)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Strahinić-Belovari, Tatjana ; Jurić-Lekić, Gordana ; Bulić-Jakuš, Floriana ; Ježek, Davor ; Marić, Svjetlana ; Vlahović, Maja ; Šerman, Draško Serum-free culture of mammalian embryo does not restrict developmental potential for differentiation of skin appendages // Acta Dermatovenerologica Croatica, 6 (1998), 1; 71-72

Podaci o odgovornosti

Strahinić-Belovari, Tatjana ; Jurić-Lekić, Gordana ; Bulić-Jakuš, Floriana ; Ježek, Davor ; Marić, Svjetlana ; Vlahović, Maja ; Šerman, Draško

engleski

Serum-free culture of mammalian embryo does not restrict developmental potential for differentiation of skin appendages

We were investigating whether mammalian epidermis which differentiates in embryo culture in vitro retains the ability to give rise to skin appendages in a richer environment in vivo. Epidermis differentiated only after 14 days of culture and was mostly terminally differentiated. Only after subsequent grafting of cultured explants under the kidney capsule skin appendages (hair and sebaceous glands) differentiated. So far no difference in their incidence related to previous medium supplementation or culture period was discovered. It seems that developmental potential of epidermis to give rise to skin appendages was not harmed by previous culture in serum-free and protein-free medium.

rat embryo; serum-free culture; graft; skin appendages

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Podaci o izdanju

6 (1)

1998.

71-72

objavljeno

1330-027X

Povezanost rada

Temeljne medicinske znanosti

Indeksiranost