engleski

Quantitative aspects of destruction of haemopoietic tissue in mouse radiation chimaeras

Marrow cells formed nodules on the spleens ; lymph node cells inhibited formation of the nodulesif admixed in a sufficiently high ratio. The ratio required for complete obliteration of the colonies dependent on antigenic disparity between the host and the donor, rather than on the size of the host. This technique allowes quantitation of the destructive effect of GVH reaction on haemopoietic tissue, its primary target.

GVHR ; CFU ; radiation chimaeras ; mice

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