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Pregled bibliografske jedinice broj: 306845

Antioxidant properties of ganglioside micelles


Gavella, Mirjana; Kveder, Marina; Lipovac, Vaskresenija; Jurašin, Darija; Filipović-Vinceković, Nada
Antioxidant properties of ganglioside micelles // Free Radical Research, 41 (2007), 10; 1143-1150 doi:10.1080/10715760701618245 (međunarodna recenzija, članak, znanstveni)


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Naslov
Antioxidant properties of ganglioside micelles

Autori
Gavella, Mirjana ; Kveder, Marina ; Lipovac, Vaskresenija ; Jurašin, Darija ; Filipović-Vinceković, Nada

Izvornik
Free Radical Research (1071-5762) 41 (2007), 10; 1143-1150

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Gangliosides ; micelles ; free radicals ; antioxidants ; electron paramagnetic resonance ; Zeta potential

Sažetak
Antioxidant activity of gangliosides GM1 and GT1b in the Fenton type of reaction was investigated by EPR spectroscopy using DMPO as a spin trap. Hydroxyl radical spin adduct signal intensity was significantly reduced in the presence of gangliosides at their micellar concentrations. Mean micellar hydrodynamic diameter was not changed, whereas significant changes in negative Zeta potential values were observed as evidenced by Zetasizer Nano ZS. This study showed that the primary mode of ganglioside action was not due to direct scavenging of OH· , but rather to the inhibition of hydroxyl radical formation. This phenomenon is related to the ability of ganglioside micelles to bind oppositely charged ferrous ions, thus reducing their concentration and consequently inhibiting OH· formation.

Izvorni jezik
Engleski

Znanstvena područja
Fizika, Kemija, Biologija



POVEZANOST RADA


Projekti:
045-0000000-0174 - Humana reprodukcija-biološki i biofizički čimbenici funkcije membrane spermija (Gavella, Mirjana, MZOS ) ( POIROT)
098-0982915-2939 - Molekulska struktura i dinamika sustava s paramagnetskim česticama (Ilakovac-Kveder, Marina, MZOS ) ( POIROT)
098-0982915-2949 - Površinski aktivne tvari, procesi u otopinama i na međupovršinama (Dutour Sikirić, Maja, MZOS ) ( POIROT)

Ustanove:
Klinika za dijabetes, endokrinologiju i bolesti metabolizma Vuk Vrhovac,
Institut "Ruđer Bošković", Zagreb

Citiraj ovu publikaciju

Gavella, Mirjana; Kveder, Marina; Lipovac, Vaskresenija; Jurašin, Darija; Filipović-Vinceković, Nada
Antioxidant properties of ganglioside micelles // Free Radical Research, 41 (2007), 10; 1143-1150 doi:10.1080/10715760701618245 (međunarodna recenzija, članak, znanstveni)
Gavella, M., Kveder, M., Lipovac, V., Jurašin, D. & Filipović-Vinceković, N. (2007) Antioxidant properties of ganglioside micelles. Free Radical Research, 41 (10), 1143-1150 doi:10.1080/10715760701618245.
@article{article, year = {2007}, pages = {1143-1150}, DOI = {10.1080/10715760701618245}, keywords = {Gangliosides, micelles, free radicals, antioxidants, electron paramagnetic resonance, Zeta potential}, journal = {Free Radical Research}, doi = {10.1080/10715760701618245}, volume = {41}, number = {10}, issn = {1071-5762}, title = {Antioxidant properties of ganglioside micelles}, keyword = {Gangliosides, micelles, free radicals, antioxidants, electron paramagnetic resonance, Zeta potential} }
@article{article, year = {2007}, pages = {1143-1150}, DOI = {10.1080/10715760701618245}, keywords = {Gangliosides, micelles, free radicals, antioxidants, electron paramagnetic resonance, Zeta potential}, journal = {Free Radical Research}, doi = {10.1080/10715760701618245}, volume = {41}, number = {10}, issn = {1071-5762}, title = {Antioxidant properties of ganglioside micelles}, keyword = {Gangliosides, micelles, free radicals, antioxidants, electron paramagnetic resonance, Zeta potential} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • Chemical Abstracts
  • Excerpta Medica
  • Index Medicus


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