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Pregled bibliografske jedinice broj: 303989

Specific sensing of poly G by the aluminum– salophen complex


Cametti, Massimo; Piantanida, Ivo; Žinić, Mladen; Dalla Cort, Antonella; Mandolini, Luigi; Marjanović, Marko; Kralj, Marijeta
Specific sensing of poly G by the aluminum– salophen complex // Journal of Inorganic Biochemistry, 101 (2007), 8; 1129-1132 (međunarodna recenzija, članak, znanstveni)


Naslov
Specific sensing of poly G by the aluminum– salophen complex

Autori
Cametti, Massimo ; Piantanida, Ivo ; Žinić, Mladen ; Dalla Cort, Antonella ; Mandolini, Luigi ; Marjanović, Marko ; Kralj, Marijeta

Izvornik
Journal of Inorganic Biochemistry (0162-0134) 101 (2007), 8; 1129-1132

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Salophen-metal complex; DNA; RNA; aluminum

Sažetak
The Al(III)– salophen complex 1 exhibited strong spectroscopic changes specifically upon addition of polyG and GpG, while double stranded DNA and RNA, and single stranded polyA, polyU and polyC induced negligible spectral changes of 1. Titrations with mononucleotides yielded no spectroscopic changes, revealing that there must be at least two consecutive guanines in single stranded oligonucleotide structure for a measurable spectroscopic change of 1. Preliminary results show that 1 has moderate antiproliferative effect on a number of human tumour cell lines.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Temeljne medicinske znanosti



POVEZANOST RADA


Projekt / tema
098-0982464-2514 - Uloga različitih mehanizama odgovora stanica na terapiju oštećenjem DNA (Marijeta Kralj, )
098-0982904-2912 - Samo-udruživanje u gelovima i sinteza funkcionalnih hibridnih materijala (Leo Frkanec, )
098-0982914-2918 - Dizajn, sinteza i ispitivanje interakcija malih molekula s DNA, RNA i proteinima (Ivo Piantanida, )

Ustanove
Institut "Ruđer Bošković", Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • Biological Abstracts
  • Chemical Abstracts
  • Index Medicus