engleski

Eco-friendly synthesis and biological evaluation of new quinoline-based dialkyl alpha-aminophosphonates

The eco-friendly synthesis and preliminary biological evaluation of new dialkyl 2- and 3-quinoline-substituted alpha-aminophosphonates have been described. The conventional and microwave-assisted one- and two-steps reactions of the appropriate aromatic aldehyde, amine and dialkyl phosphite, carried out without or in the presence of solvent and catalyst, have been compared and discussed.

alpha-aminophosphonate; quinoline; dialkyl phosphite; cytostatic activity; antiviral activity; microwave-assisted reaction

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