engleski

Regiospecific Synthesis Trifluormethyl Substituted Dibenzosemibullvalenes

In connection with our previous studies of chiral dibenzosemibullvalenes, we have prepared the novel regiospecifically trifluoromethyl substituted dibenzosemibullvalenes (6) and (8). This compounds were synthesized for their pharmacological evaluation on antidepressive activities. The stereostructure of (8) was unequivocally determined by X-ray crystalographic analysis.

regiospecific synthesis; dibenzosemibullvalenes

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