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Pregled bibliografske jedinice broj: 281061

Kliničke i patohistološke karakteristike biopsijom dokazanih bubrežnih bolesti djece u Hrvatskoj


Batinić, Danica; Šćukanec-Špoljar, Mira; Milošević, Danko; Šubat-Dežulović, Mirna; Saraga, Marijan; Đelmiš, Jasna; Puretić, Zvonimir; Cvitković-Kuzmić, Andrea; Skitarelić, Nataša; Spajić, Marija et al.
Kliničke i patohistološke karakteristike biopsijom dokazanih bubrežnih bolesti djece u Hrvatskoj // Acta medica Croatica, 61 (2007), 4; 361-364 (međunarodna recenzija, članak, znanstveni)


Naslov
Kliničke i patohistološke karakteristike biopsijom dokazanih bubrežnih bolesti djece u Hrvatskoj
(Clinical and pathohistological characteristics of biopsy proven renal diseases of children in Croatia)

Autori
Batinić, Danica ; Šćukanec-Špoljar, Mira ; Milošević, Danko ; Šubat-Dežulović, Mirna ; Saraga, Marijan ; Đelmiš, Jasna ; Puretić, Zvonimir ; Cvitković-Kuzmić, Andrea ; Skitarelić, Nataša ; Spajić, Marija ; Nižić, Ljiljana, Vrljičak, Kristina ; Matković, Maja ; Kniewald, Hrvoje ; Batinić, Danko ; Grković, Lana ; Borojević, Irena ; Flajšman, Sanja ; Košuljandić-Vukić, Đurđica ; Ćorić, Marijana ; Glavina-Dundov, M. ; Đorđević, Gordana ; Bazina, M. ; Marić, Šemsa ; Ljubanović, Danica

Izvornik
Acta medica Croatica (1330-0164) 61 (2007), 4; 361-364

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
nacionalni registar bubrežnih bolesti djece ; klinička slika ; morfološka dijagnostika ; epidemiologija glomerularnih bolesti
(national registry of renel diseases in children ; epidemiology of glomerular disease in children)

Sažetak
There is little data on the spectrum of renal diseases in children in Croatia. The Croatian Society for Pediatric Nephrology has established the Registry of Biopsy-Proven Renal Diseases in an attempt to address this issue nationwide. Here we report preliminary results of a retrospective analysis of clinical and histopathological data of 565 children aged < or =17 years presenting to 9 hospitals in Croatia from 1991 to 2004, in whom kidney biopsy was performed. The most common indication for renal biopsy was nephrotic syndrome (39.1%), followed by asymptomatic proteinuria/hematuria (22.0%) and acute nephritic syndrome (17.0%). All biopsies were analysed by light-, immunofluorescent and electron microscopy. The majority of children, 552 out of 565 (92.4%), had glomerulonephritis (GN). Tubulointerstitial nephritis was found in 16 (2.8%), congenital renal parenchyma anomalies in 14 (2.5%) and vascular disease in 11 (1.9%) cases. One (0.2%) child had sarcoidosis with nephrocalcinosis. The sample was non-diagnostic in 1 (0.2%) case. Among children with GN, primary GN accounted for 70.9%, secondary GN for 16.1% and hereditary GN for 13.0% cases. The most frequent primary GN forms were focal segmental glomerulosclerosis (FSGS) (24.6%), mesangial proliferative glomerulonephritis (MEPGN) (19.2%) and IgA nephropathy (18.1%). Acute GN in resolution was found in 11.1% and minimal changes GN in 6.8% of cases. Most children with secondary GN had nephritis of Henoch-Schonlein purpura (HSP) (54.7%) and nephritis of systemic lupus erythematosus (SLE) (40.5%), while among hereditary GN Alport syndrome was most common (80.9%). In the group of children with primary GN who presented with nephrotic syndrome, most common forms were FSGS (38.5%) and MEPGN (24.0%). Minimal changes GN accounted for only 10.9% of cases. IgA nephropathy, primary or related to HSP (20.0%), FSGS (16.1%), MEPGN (12.6%) and Alport syndrome (9.7%) were the most common biopsy-proven renal diseases in Croatian children. The analysis provided data on the frequency of histological renal lesions in children in Croatia. The higher frequency of FSGS and MEPGN among Croatian children in comparison with other countries deserves further evaluation

Izvorni jezik
Hrvatski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove
Medicinski fakultet, Rijeka,
Opća bolnica Zadar,
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice",
KBC Split,
Klinička bolnica "Dubrava",
Klinički bolnički centar Zagreb,
Medicinski fakultet, Split,
Klinički bolnički centar Rijeka,
Opća bolnica Karlovac

Citiraj ovu publikaciju

Batinić, Danica; Šćukanec-Špoljar, Mira; Milošević, Danko; Šubat-Dežulović, Mirna; Saraga, Marijan; Đelmiš, Jasna; Puretić, Zvonimir; Cvitković-Kuzmić, Andrea; Skitarelić, Nataša; Spajić, Marija et al.
Kliničke i patohistološke karakteristike biopsijom dokazanih bubrežnih bolesti djece u Hrvatskoj // Acta medica Croatica, 61 (2007), 4; 361-364 (međunarodna recenzija, članak, znanstveni)
Batinić, D., Šćukanec-Špoljar, M., Milošević, D., Šubat-Dežulović, M., Saraga, M., Đelmiš, J., Puretić, Z., Cvitković-Kuzmić, A., Skitarelić, N. & Spajić, M. (2007) Kliničke i patohistološke karakteristike biopsijom dokazanih bubrežnih bolesti djece u Hrvatskoj. Acta medica Croatica, 61 (4), 361-364.
@article{article, year = {2007}, pages = {361-364}, keywords = {national registry of renel diseases in children, epidemiology of glomerular disease in children}, journal = {Acta medica Croatica}, volume = {61}, number = {4}, issn = {1330-0164}, title = {Clinical and pathohistological characteristics of biopsy proven renal diseases of children in Croatia}, keyword = {national registry of renel diseases in children, epidemiology of glomerular disease in children} }

Časopis indeksira:


  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • EMBASE (Excerpta Medica)
  • MEDLINE