engleski

Modern aspects in bone tumor treatment

Current treatment strategies for primary malignant bone tumors draw on chemotherapy, surgery, and radiotherapy alone or in combination. The detailed strategy depends on many factors that are evaluated by the oncology team responsible for treating the patient. A typical approach would involve the administration of chemotherapeutic agents prior to surgery followed by further chemotherapy after surgery. The pre-surgery treatment is aimed at shrinking the tumor volume in order to reduce the amount of tissue removal during surgery. The chemotherapy after surgery is for suppressing tumor reoccurrence in the event that some tumor cells remain. With recurrent or metastatic primary malignant bone tumors several operations may be performed with the administration of chemotherapy agents over a long period of time. Surgical treatment is the most important in the treatment of bone tumors. Surgical removal of the tumor is common when it is operable. The surgeon has to consider the best surgical option depending on the site and size of the tumor but also on the patient's age and the overall prognosis. Current surgical practice seeks to minimize the impact on the patient's life style. Limb-sparing techniques, such as using artificial joints or other endoprostheses, and allografting, are now a viable alternative to amputation and radical surgery when the patient's medical condition permits. Allografting of bone and joint is a good and workable method in repairing and reconstructing the bone defect due to the excision of bone tumor. Limb-sparing techniques preserve a greater degree of natural function than do amputation or radical surgery without reducing the chance of patient survival.

bone tumor; treatment

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