engleski

Contribution of consanguinuity to polygenic and multifactorial diseases

The favorable secular trends in health and life expectancy in human populations worldwide during recent decades coincides both with improved economic growth and development and with massive urbanization, admixture and outbreeding on a global scale. These observed health gains are not solely explained by socioeconomic factors. Therefore, until this issue is better understood, the possible contribution of consanguinity and outbreeding to polygenic traits and complex human diseases should not be dismissed, and the Arab countries are well-placed to be at the forefront of this endeavor.

consanguinity; late onset disease

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