engleski

Is Obesity a Risk Factor for Severe Alcoholic Acute Pancreatitis?

Introduction: Obesity has been associated with worse prognosis in acute pancreatitis (AP) favouring the development of complications. We aimed to evaluate the association between obesity and severity of pancreatitis according to Atlanta criteria in patients with the first attack of alcoholic AP. Patients and Methods: We reviewed medical records of 584 patients with the first attack of AP admitted to our hospital centre during the last ten years. Among them, 106 patients had acute pancreatitis of alcoholic etiology. Those patients were classified according to the body mass index (BMI) in normal weight (BMI 25 kg/m2) and overweight (BMI  25 kg/m2) group consisting of 51 and 55 patients respectively. Results: In a normal weight group 54% (28/51) of patients developed severe AP, while in an overweight group 45% (25/55) of patients presented with the severe form of disease. Accordingly, in patients with alcoholic etiology of AP the risk for development of severe AP was significantly decreased following increase of BMI (relative risk (RR) 0.55 ; 95% confidence interval (CI) 0.41– 0.74). Conclusion: Although obesity is considered as a risk factor for development of severe AP, our study showed that increased BMI in a group of patients with alcoholic etiology decreases that risk.

acute pancreatitis; obesity

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