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Pregled bibliografske jedinice broj: 270888

Dissolution of celecoxib from mucoadhesive disks based on polyaspartamide derivatives


Ballian Krznar, Davorka; Filipović-Grčić, Jelena; Zorc, Branka; Zovko, Marijana
Dissolution of celecoxib from mucoadhesive disks based on polyaspartamide derivatives // Acta Pharmaceutica, 56 (2006), 4; 463-471 (međunarodna recenzija, članak, znanstveni)


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Naslov
Dissolution of celecoxib from mucoadhesive disks based on polyaspartamide derivatives

Autori
Ballian Krznar, Davorka ; Filipović-Grčić, Jelena ; Zorc, Branka ; Zovko, Marijana

Izvornik
Acta Pharmaceutica (1330-0075) 56 (2006), 4; 463-471

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
celecoxib; disks; polyaspartamide; thiomer

Sažetak
A series of mucoadhesive disks with celecoxib as a model drug of very low aqueous solubility were prepared and characterized. Two polymers of polyaspartamide type, poly  ,  -(N-2-hydroxyethyl-DL-aspartamide) (PHEA, 1) and its thiolated analogue poly[α , β -(N-2-hydroxyethyl-DL-aspartamide)]-poly[α , β -(N-2-thioethyl-DL-aspartamide)] copolymer (PHTA, 2a, b), and two commercially available polymers Carbopol 934P and hydroxypropylmethyl cellulose 4000 were used as excipients. Disks containing a mixture of equivalent amounts of thiomer 2b and Carbopol 934P as an excipient exhibited the highest dissolution rate.

Izvorni jezik
Engleski

Znanstvena područja
Farmacija



POVEZANOST RADA


Citiraj ovu publikaciju

Ballian Krznar, Davorka; Filipović-Grčić, Jelena; Zorc, Branka; Zovko, Marijana
Dissolution of celecoxib from mucoadhesive disks based on polyaspartamide derivatives // Acta Pharmaceutica, 56 (2006), 4; 463-471 (međunarodna recenzija, članak, znanstveni)
Ballian Krznar, D., Filipović-Grčić, J., Zorc, B. & Zovko, M. (2006) Dissolution of celecoxib from mucoadhesive disks based on polyaspartamide derivatives. Acta Pharmaceutica, 56 (4), 463-471.
@article{article, year = {2006}, pages = {463-471}, keywords = {celecoxib, disks, polyaspartamide, thiomer}, journal = {Acta Pharmaceutica}, volume = {56}, number = {4}, issn = {1330-0075}, title = {Dissolution of celecoxib from mucoadhesive disks based on polyaspartamide derivatives}, keyword = {celecoxib, disks, polyaspartamide, thiomer} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • Chemical Abstracts
  • Excerpta Medica





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