engleski

Relationship of HBA1c level and smoking to periodontal status in a cohort of Croatian patients with insulin-dependent diabetes mellitus

Background: There is firmly established correlation between periodontitis and diabetes mellitus (DM), but it is still unknown how does the duration of DM influence the periodontal status of individuals. Aim: The aim of the study was to investigate the effect of DM duration and HbA1c level on periodontal status of patients with insulin-dependent DM, as well as the combined effect of smoking and HbA1c level on periodontal status. Materials and methods: Subjects were randomly selected from the patients with insulin-dependent DM that are treated at the Department of Endocrinology in the hospital « ; Sveti Duh» ; . Data was gathered by means of an interview, clinical periodontal investigation and patients
charts from the department. Sites with probing depth of 5 mm and greater were selected as sites with periodontitis. By means of Poisson regression model a relative risk with 95% confidence interval was computed, corrected for age of the subjects. Results: Relative risk for attachment loss in smokers was 12.805 and for probing depth in smokers 7.99. Relative risk of the HbA1c level >8.5 in smokers were 10.681 (P = 0.002), and 8.214 (P = 0.006) for HbA1c level £ ; 8.5. Relative risk for attachment loss in nonsmokers was 4.891 (P = 0.031). Conclusion: It was concluded that insulin-dependent smokers with poor glycaemic control have the greatest risk for development and progression of periodontal disease.

HBA1c level; smoking; periodontal status

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