Streptozotocin-intracerebroventricularly treated rats: behavioral, neurochemical and structural resembling to the human sporadic type of Alzheimer's disease (CROSBI ID 521423)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Salkovic-Petrisic, Melita ; Tribl, Florian ; Osmanovic, Jelena ; Schmidt, Manuela ; Hoyer, Siegfried ; Riederer, Peter
engleski
Streptozotocin-intracerebroventricularly treated rats: behavioral, neurochemical and structural resembling to the human sporadic type of Alzheimer's disease
Streptozotocin-intracerebroventricularly treated rats (STZ-icv) have become an experimental model of sporadic Alzheimer's disease, and demonstrate resembling in cognitive deficits, alterations of Akt/PKB and GSK-3 enzymes of insulin receptor signaling cascade in the brain, as well as alterations of tau protein and accumulation of beta amyloid like aggregates in the brain.
streptozotocin; Alzheimer's disease; brain; Akt/PKB; GSK-3
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Podaci o prilogu
S238-x.
2006.
objavljeno
Podaci o matičnoj publikaciji
Alzheimer's & Dementia (supplement): Abstracts
Iqbal K, Winblad B
New York (NY): Elsevier
Podaci o skupu
10th International Conference on Alzheimer's Disease and Related Disorders
poster
15.07.2006-20.07.2006
Madrid, Španjolska
