engleski

Gastrointestinal melanoma : review of the computer data base in the period 1996-2005.

Malignant melanoma is very rare in the gastrointestinal system ; it comprises about 0.2- 3% of all melanomas and has extremely poor prognosis. Surgical treatment ranges from radical resection with lymphadenectomy to local excision alone. Primary melanoma is most frequently found in anorectal region of the gastrointestinal system. Aim of the study was to analyze frequency and sites of primary gastrointestinal melanoma in our bioptic material collected during a 10 year period. We used the computer database from Ljudevit Jurak University Department of Pathology and Surgical Department, Sestre milosrdnice University Hospital, Zagreb in the time period from 1996 to 2005. During the analyzed period there were 2831 patients (M:F=1748:1083) with diagnosed gastrointestinal tumors. Female patients were between 22-86 years old (mean 62, 0) while males were between 26-84 (mean 68, 0). In the examined time period malignant melanoma was diagnosed only in 16 (0, 6 %) patients (M:F=12:4). At the time of diagnosis male patients with melanoma were between 22-79 years old (mean 54, 0), while females were between 42– 70 (mean 59, 0). Out of all patients with gastrointestinal melanomas only 5 (31.3%) cases (M:F=3:2) were primary gastrointestinal, while 11 (68.7%) cases were metastases from skin melanoma. Two cases of primary melanomas in gastrointestinal system were originated from gallbladder (M:F=1:1), while 3 cases were diagnosed in the anorectal region (M:F=3:1). Female patients with primary gastrointestinal melanoma were 52 and 57 years old, while males were between 52 and 75 (mean 66, 0). Metastastatic melanomas usually involved small intestine (9/11 cases), while only one case was found in stomach and one case in colon. Although primary gastrointestinal melanomas are very rare, they are almost never suspected on clinical examination. In our bioptic material primary melanomas were found in anorectal region and gallbladder, while metastatic melanomas were usually found in the small intestine.

Gastrointestinal melanoma

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