engleski

Transfusion of one unit of red blood cells

The aim of the study was to determine whether the transfusion of one unit of red blood cells (RBC) is true criterion for poor patient care. Medical records of 148 patients (pts) who received transfusion of one RBC unit at the Department of Medicine in the period from 1997 to 2000 were retrospectivly studied. The study included 148 pts, 76 (51.4%) males, 72 (48.6%) females, mean age 66.88+/-14.56 years. Pretransfusion mean haemoglobin (Hb) value (Hb1) was 85.0+/-12.0 (mod 78) g/L, increasing to 96.9+/-11.8 (mod 90) g/L (Hb2) after transfusion and the last measured value Hb3 was 98.2+/-13.4 (mod 102) g/L. The differences between the Hb2 and Hb1 values statistically differed considerably from the differences between the Hb3 and Hb1 values (p=0.001). Between the living and deceased patients statistically significant was the difference in the distribution of differences between Hb2 and Hb1 (p=0.028) and Hb3 and Hb1 (p=0.001) according to the disease outcome. Significant were the differences between arterial oxygen tension (PaO2) at Hb1 and Hb2 (p=0, 0001), as well as between the arterial oxygen saturation (SaO2) at the Hb1 and Hb2 values (p=0, 0001). There is no strict clinical indication for one unit of RBC transfusion. Determinants of the need and amount of RBC transfusion except hemoglobin value include the etiology and chronicity of anemia, patient’ s ability to compensate for decreased oxygen carrying capacity and tissue oxygen requirements.

hemoglobin; transfusion of one RBC unit; outcome

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