Napredna pretraga

Pregled bibliografske jedinice broj: 264331

Hemochromatosis gene mutations in patients with alcoholic cirrhosis


Starčević Eizmerević, Nada; Stepec, Srećko; Ristić, Smiljana; Milić, Sandra; Brajenović -Milić, Bojana; Štimac, Davor; Kapović, Miljenko; Peterlin, Borut
Hemochromatosis gene mutations in patients with alcoholic cirrhosis // Clinical genetics, 70 (2006), 3; 257-259 (međunarodna recenzija, pismo, znanstveni)


Naslov
Hemochromatosis gene mutations in patients with alcoholic cirrhosis

Autori
Starčević Eizmerević, Nada ; Stepec, Srećko ; Ristić, Smiljana ; Milić, Sandra ; Brajenović -Milić, Bojana ; Štimac, Davor ; Kapović, Miljenko ; Peterlin, Borut

Izvornik
Clinical genetics (0009-9163) 70 (2006), 3; 257-259

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pismo, znanstveni

Ključne riječi
Hemochromatosis; gene mutations; alcoholic cirrhosis

Sažetak
We have investigated the contribution of genetic polymorphisms in the hemochromatosis gene to susceptibility for alcoholic liver disease in Croatian and Slovenian patients. The genotypes of alcoholics with and without cirrhosis, and healthy controls for the polymorphisms C282Y, H63D, and S65C suggested that C282Y and S65C mutations were not associated to the risk of developing alcoholic cirrhosis in our populations, while the frequency of H63D heterozygotes was significantly higher (P=0.0019) in patients with alcoholic cirrhosis (31.98%) than in healthy controls (19.14%).

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE