Detection Of Human Papillomavirus (HPV) Type 45, 52 And 58 In Cervical Specimens (CROSBI ID 520656)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa
Podaci o odgovornosti
Halec, Gordana ; Sabol, Ivan ; Grce, Magdalena
engleski
Detection Of Human Papillomavirus (HPV) Type 45, 52 And 58 In Cervical Specimens
Infection with human papillomavirus (HPV) has been implicated as the main and sole cause of cervical cancer. However, only a subset of high risk (HR ; with high oncogenic potential) HPV types are implicated in cervical cancerogenesis. Worldwide, the most frequently found HR HPV is type 16 that accounts for more than 60% of cases of cervical cancer. In Europe, HPV 18, 33, 31 and 45 are the next frequently found HR HPVs in cervical cancer specimens. HPV 52 and 58 are less frequent in Europe but not uncommon worldwide, especially in Asia. The aim of this study was to evaluate the prevalence of HR HPV 45, 52 and 58 among women with cytological abnormalities, which were already tested HPV positive by consensus primers directed polymerase chain reaction (PCR) but negative by type-specific primers directed PCR for HPV 6/11, 16, 18, 31 and/or 33 (Grce M et al., Anticancer Res 2001 ; 21: 579-584.). Herein, we also used type-specific primers directed PCR for detection of HPV 45, 52 and 58 in archival DNA isolated from cervical specimens. Out of 2, 150 specimens, 61% and 39% was HPV DNA positive and negative, respectively. Our preliminary results indicate that HPV 16 is the most common, while HPV 31 is the second most common HR HPV type in this study group. The prevalence of each HPV type including HPV 6/11, 16, 31, 33, 45, 52 and 58 will be presented.
HPV
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o prilogu
120-x.
2006.
nije evidentirano
objavljeno
Podaci o matičnoj publikaciji
Ninth International Summer School on Biophysics - Book of Abstracts
Pifat-Mrzljak, Greta ; Ilakovac Kveder, Marina
Zagreb: Institut Ruđer Bošković
Podaci o skupu
Ninth International Summer School on Biophysics - Supramolecular Structure and Function
poster
16.09.2006-28.09.2006
Rovinj, Hrvatska