Pregled bibliografske jedinice broj: 262908
Detection Of Human Papillomavirus (HPV) Type 45, 52 And 58 In Cervical Specimens
Detection Of Human Papillomavirus (HPV) Type 45, 52 And 58 In Cervical Specimens // Ninth International Summer School on Biophysics - Book of Abstracts / Pifat-Mrzljak, Greta ; Ilakovac Kveder, Marina (ur.).
Zagreb: Ruđer Bošković Institute, 2006. (poster, nije recenziran, sažetak, znanstveni)
CROSBI ID: 262908 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Detection Of Human Papillomavirus (HPV) Type 45, 52 And 58 In Cervical Specimens
Autori
Halec, Gordana ; Sabol, Ivan ; Grce, Magdalena
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Ninth International Summer School on Biophysics - Book of Abstracts
/ Pifat-Mrzljak, Greta ; Ilakovac Kveder, Marina - Zagreb : Ruđer Bošković Institute, 2006
Skup
Ninth International Summer School on Biophysics - Supramolecular Structure and Function
Mjesto i datum
Rovinj, Hrvatska, 16-28.09.2006
Vrsta sudjelovanja
Poster
Vrsta recenzije
Nije recenziran
Ključne riječi
HPV
Sažetak
Infection with human papillomavirus (HPV) has been implicated as the main and sole cause of cervical cancer. However, only a subset of high risk (HR ; with high oncogenic potential) HPV types are implicated in cervical cancerogenesis. Worldwide, the most frequently found HR HPV is type 16 that accounts for more than 60% of cases of cervical cancer. In Europe, HPV 18, 33, 31 and 45 are the next frequently found HR HPVs in cervical cancer specimens. HPV 52 and 58 are less frequent in Europe but not uncommon worldwide, especially in Asia. The aim of this study was to evaluate the prevalence of HR HPV 45, 52 and 58 among women with cytological abnormalities, which were already tested HPV positive by consensus primers directed polymerase chain reaction (PCR) but negative by type-specific primers directed PCR for HPV 6/11, 16, 18, 31 and/or 33 (Grce M et al., Anticancer Res 2001 ; 21: 579-584.). Herein, we also used type-specific primers directed PCR for detection of HPV 45, 52 and 58 in archival DNA isolated from cervical specimens. Out of 2, 150 specimens, 61% and 39% was HPV DNA positive and negative, respectively. Our preliminary results indicate that HPV 16 is the most common, while HPV 31 is the second most common HR HPV type in this study group. The prevalence of each HPV type including HPV 6/11, 16, 31, 33, 45, 52 and 58 will be presented.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
