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Pregled bibliografske jedinice broj: 262018

Salivary interleukin 6 and tumor necrosis factor α in patients with recurrent aphthous ulceration


Vučićević-Boras, Vanja; Lukač, Josip; Brailo, Vlaho; Picek, Pavle; Kordić, Darka; Žiić-Alajbeg, Iva; Blažić-Potočki, Zita
Salivary interleukin 6 and tumor necrosis factor α in patients with recurrent aphthous ulceration, 2006. (poster, nije recenziran, sažetak, znanstveni)


Naslov
Salivary interleukin 6 and tumor necrosis factor α in patients with recurrent aphthous ulceration

Autori
Vučićević-Boras, Vanja ; Lukač, Josip ; Brailo, Vlaho ; Picek, Pavle ; Kordić, Darka ; Žiić-Alajbeg, Iva ; Blažić-Potočki, Zita

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Mjesto i datum
,

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
recurrent aphthous ulcerations; interleukin 6; tumor necrosis factor alpha; saliva

Sažetak
Background: Recurrent apthous ulceration (RAU) is a well known oral disease which seems to be mediated principally by the immune system. However, it is still a matter of debate which part of the immune system is implicated in its pathogenesis as a reaction to the still unknown antigen. The aim of this study was to evaluate salivary cytokines, interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-&#945; ) in RAU patients. Methods: In 26 patients with minor RAU, age range 23-49, mean 27.3 yrs, during both the acute phase and remission and in 26 healthy controls, age range 22-64, mean 30.1 yrs., salivary IL-6 and TNF-&#945; levels were determined by use of ELISA. Statistical analysis was performed by use of descriptive statistics. Results: Significant differences in salivary TNF-&#945; between healthy controls and patients with acute RAU and during the remission period were found (p<0.001) as well as between patients with acute RAU and those during the remission period (p<0.001). No differences in salivary IL-6 between all three groups could be found. Conclusions: We might conclude that elevated salivary TNF-&#945; levels during acute RAU and especially during the remission period are of importance in RAU, whereas salivary IL-6 levels seem not to play a role in the RAU disease. Relevance: Salivary TNF-&#945; could be used as marker of disease activity in RAU patients. However, further studies on larger number of patients are required.

Izvorni jezik
Engleski

Znanstvena područja
Dentalna medicina



POVEZANOST RADA


Projekt / tema
0065008
0134011

Ustanove
Stomatološki fakultet, Zagreb

Citiraj ovu publikaciju

Vučićević-Boras, Vanja; Lukač, Josip; Brailo, Vlaho; Picek, Pavle; Kordić, Darka; Žiić-Alajbeg, Iva; Blažić-Potočki, Zita
Salivary interleukin 6 and tumor necrosis factor α in patients with recurrent aphthous ulceration, 2006. (poster, nije recenziran, sažetak, znanstveni)
Vučićević-Boras, V., Lukač, J., Brailo, V., Picek, P., Kordić, D., Žiić-Alajbeg, I. & Blažić-Potočki, Z. (2006) Salivary interleukin 6 and tumor necrosis factor α in patients with recurrent aphthous ulceration. U: .
@article{article, year = {2006}, pages = {14}, keywords = {recurrent aphthous ulcerations, interleukin 6, tumor necrosis factor alpha, saliva}, title = {Salivary interleukin 6 and tumor necrosis factor and \#945; in patients with recurrent aphthous ulceration}, keyword = {recurrent aphthous ulcerations, interleukin 6, tumor necrosis factor alpha, saliva} }