engleski

URINARY 6-SULFATOXYMELATONIN EXCRETION IN RATS AFTER MICROWAVE IRRADIATION

Aim of this study was to examine whether 2.45 GHz irradiation has effects on rats’ nocturnal urinary 6- sulfatoxymelatonin (6SM) excretion. Urinalysis parameters after whole-body exposure of two hours per day, five days a week, throughout fifteen days lasting experiment was followed-up. The average specific absorption rate (SAR) was calculated to 1.25 (&plusmn ; 0.36) W/kg. The concentration of 6SM in urine samples was determined by direct radioimmunoassay kit (Stockgrand Ltd., Guildford, UK). Urinary glucose, bilirubin, ketones, specific gravity, blood, pH, protein, urobilinogen, nitrite and leukocytes appearance has been accomplished by means of multiple reagent strips (N-Multistix&reg ; Bayer Diagnostic, UK). In comparison to the sham-exposed group, no significant changes in body temperature or food and water intake were observed. Delayed significant decline in 6SM of irradiated rats has been obtained between days eight and eleven. Until the end of experiment 6SM level remained low. The results of urinary pH, glucose, bilirubin, ketones, specific gravity, blood, protein, urobilinogen, nitrite, leukocyte appearance in the urine indicated no significant differences between treated and control group. In conclusion: it is likely that applied microwave field poses capacity to affect the hormone melatonin balance in rats after repeated exposure.

2.45 GHz; nocturnal urinary 6-sulfatoxymelatonin; rats

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