engleski

Loss of heterozygosity of the APC gene found in a single case of oligoastrocytoma

This study analyses APC gene (Adenomatous polyposis coli) in a 29-year-old female patient with oligoastrocytoma. Oligoastrocytoma sample was tested for gene instability by PCR/loss of heterozygosity using RFLP method. Allelic loss of the APC gene was found in our patient. We wanted to inform you on this interesting finding which may contribute to better understanding of oligoastrocytoma genetic profile.

oligoastrocytoma; APC gene; loss of heterozygosity

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