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Pregled bibliografske jedinice broj: 258902

Correlation of structure and retention behaviour in reversed-phase high-performance liquid chromatography. II. Methionine-enkephalin-related glycoconjugates


Varga-Defterdarović, Lidija; Horvat, Štefica; Skurić, Mare; Horvat, Jaroslav
Correlation of structure and retention behaviour in reversed-phase high-performance liquid chromatography. II. Methionine-enkephalin-related glycoconjugates // Journal of chromatography. A, 687 (1994), 1; 107-112 doi:10.1016/0021-9673(94)00771-3 (međunarodna recenzija, članak, znanstveni)


Naslov
Correlation of structure and retention behaviour in reversed-phase high-performance liquid chromatography. II. Methionine-enkephalin-related glycoconjugates

Autori
Varga-Defterdarović, Lidija ; Horvat, Štefica ; Skurić, Mare ; Horvat, Jaroslav

Izvornik
Journal of chromatography. A (0021-9673) 687 (1994), 1; 107-112

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
RP HPLC ; retention ; Met-enkephalin ; glycoconjugates

Sažetak
Reversed-phase high-performance liquid chromatographic elution data for methionine-enkephalin-related glycoconjugates were analysed as a function of the identity and position of the sugar-peptide linkage. It was shown that binding to the column could be correlated with the degree of sugar moiety protection. Replacement of either the phenylalanine or methionine residue in the peptide backbone of the glycoconjugates with its D-enantiomer leads to a considerably stronger retention on a reversed-phase column. The dependence of retention times on the methanol concentration in the mobile phase suggested that, under the conditions studied, there are different retention mechanisms for glycopeptides containing unprotected sugar moieties in the molecule.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
1-07-192

Ustanove
Institut "Ruđer Bošković", Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • Chemical Abstracts


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