engleski

Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts

The synthesis of racemic and enantiomerically pure N-p-methylbenzyl-3-benzamidoquinuclidinium bromides (6-8) and N-p-chlorobenzyl-3-benzamidoquinuclidinium bromides (9-11) is described. These compounds were prepared from racemic or enantiomerically pure 3-benzamidoquinuclidines (3-5) with the appropriate reagents for quaternization: p-methylbenzyl bromide (1) and p-chlorobenzyl bromide (2).

quinuclidine; N-quaternary salts; quaternization

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