engleski

Lack of Proper follicular dendritic cells networks may prevent germinal center fomation in both Bcl-3 and p52 KO mice.

Follicular dendritic cells (FDCs) are antigen-presenting cells located in B cell zones of secondary lymphoid organs.They do not process antigen, instead can capture antigen in its native form and present it for prolonged periods, a function thought to be important for generation of memory response.The cellular origin of FDC and their maturation to cells forming networks in response to antigen will be discused.

follicular dendritic cells network; NF-kB activation; germinal center formation

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