engleski

Towards an understanding of photosynthetic regulation: TROL

My current research is focused on defining the role of the thylakoid membrane protein TROL in plant Arabidopsis thaliana (L.) Heynh. We assumed that this protein is included in fine-tuning of the regulation mechanisms of photosynthesis, possibly in cyclic electron transport (CET). Apart from its possible role in CET, this protein could also be interesting from the evolutionary point of view. TROL possesses rhodanese-like domain linked to a module which interacts with FNR (Ferredoxin NADPH oxidoreductase). Rhodaneses are very old group of proteins, suggested to be involved in distinct biological functions such as cyanide detoxification, formation of prosthetic groups in iron-sulfur proteins and thiamin biosynthesis. It is presumed that all tyrosine-specific and dual-specifity phosphatases have evolved from a rhodanese-like precursor. Moreover, TROL possesses a catalytically inactive rhodanese domain, which is presumed to play a regulatory role, perhaps in connection with signaling. TROL probably evolved from enzymes involved in ancient photosynthesis. It would be interesting to see how the role of this rhodanese domain changed through the evolution and, more important, why this role changed. Since I have been more oriented onto lab work, I would like to learn more about evolutionary genomics for my future research.

regulation of photosynthesis; rhodanese; TROL

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