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Pregled bibliografske jedinice broj: 252445

Electrochemical characterization of simvastatin by abrasive stripping and square-wave voltammetry


Komorsky-Lovrić, Šebojka; Nigović, Biljana
Electrochemical characterization of simvastatin by abrasive stripping and square-wave voltammetry // Journal of Electroanalytical Chemistry, 593 (2006), 125-130 (međunarodna recenzija, članak, znanstveni)


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Naslov
Electrochemical characterization of simvastatin by abrasive stripping and square-wave voltammetry

Autori
Komorsky-Lovrić, Šebojka ; Nigović, Biljana

Izvornik
Journal of Electroanalytical Chemistry (0022-0728) 593 (2006); 125-130

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
simvastatin; statins; graphite electrode; mercury electrode; abrasive stripping voltammetry; cyclic voltammetry; square-wave voltammetry

Sažetak
The electrochemical characteristic of the lipid-lowering drug simvastatin were investigeted on graphite and mercury electrode. Solid microparticles of simvastatin were mechanically immobilized on the surface graphite electrode and immeresed into aqueous electrolyte. The microparticles were oxidized at 1.1. V in totally irreversible electrode reaction. Simvastatin dissolved in acetronitrile and admixed with 0.1 M Na2B4O7-KH2PO4 aqueous buffered solution pH 7 is strongly adsorbed of surface mercury elecreode. Adsorbed simvastatin was reduced at -1.45 V in the fast and reversible electrode reaction by a chemical reaction.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
0098123

Ustanove
Institut "Ruđer Bošković", Zagreb

Citiraj ovu publikaciju

Komorsky-Lovrić, Šebojka; Nigović, Biljana
Electrochemical characterization of simvastatin by abrasive stripping and square-wave voltammetry // Journal of Electroanalytical Chemistry, 593 (2006), 125-130 (međunarodna recenzija, članak, znanstveni)
Komorsky-Lovrić, Š. & Nigović, B. (2006) Electrochemical characterization of simvastatin by abrasive stripping and square-wave voltammetry. Journal of Electroanalytical Chemistry, 593, 125-130.
@article{article, year = {2006}, pages = {125-130}, keywords = {simvastatin, statins, graphite electrode, mercury electrode, abrasive stripping voltammetry, cyclic voltammetry, square-wave voltammetry}, journal = {Journal of Electroanalytical Chemistry}, volume = {593}, issn = {0022-0728}, title = {Electrochemical characterization of simvastatin by abrasive stripping and square-wave voltammetry}, keyword = {simvastatin, statins, graphite electrode, mercury electrode, abrasive stripping voltammetry, cyclic voltammetry, square-wave voltammetry} }

Časopis indeksira:


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  • Web of Science Core Collection (WoSCC)
    • SCI-EXP, SSCI i/ili A&HCI